The management of diarrhea caused by metformin. The CDC estimates that there are 26 million Americans living with diabetes. Roughly 90% of those cases are patients diagnosed with type 2 diabetes. Metformin definition is - a drug used in the form of its hydrochloride C4H11N5·HCl especially to treat type 2 diabetes. Risks of consuming alcohol while on Metformin. If you are used to having a glass of wine with your dinner or a can of beer now and again, you might wonder if you can continue with that habit once you are on metformin. Hello and Blessings everyone. Can anyone offer me insight to this Metformin and mood swings. I swear since my first dose It gives me such a feeling of being on edge. I started on 250mg of Metformin yesterday and today with dinner. I noticed that my lip feels slightly swollen. Not were it's uncomfortable just that it feels kinda numb. Publications. Published: July 1998. Metformin and Fatal Lactic Acidosis. Information on this subject has been updated. Read the most recent information. Metformin Hydrochloride Tablets USP are oral antihyperglycemic drugs used in the management of type 2 diabetes. Metformin hydrochloride ( N,N-dimethylimidodicarbonimidic diamide hydrochloride) is not chemically or pharmacologically related to any other classes of oral antihyperglycemic agents. Metformin, an FDA approved first-line drug for the treatment of type 2 diabetes, has known beneficial effects on glucose metabolism. Evidence from animal models and in vitro studies suggest that in addition to its effects on glucose metabolism, metformin may influence metabolic and cellular processes associated with the development of age. To address that concern, researchers recently conducted a study, published in the journal Cancer Epidemiology, Biomarkers & Prevention, of the relationship between metformin use and colorectal cancer, and they came away with some good news: Long-term use of metformin is associated with a decreased risk for colorectal cancer in men with diabetes. Metformin is a type of medication used to treat Type 2 Diabetes. Because there is a strong link between diabetes and PCOS, metformin is now commonly proscribed to treat PCOS.